Located in the state of Kentucky, Louisville/Jefferson County is the largest city in the state and the 29th most populous city in the United States. The city is situated on the Ohio River, making it an important transportation hub for both freight and passenger traffic. The city's strategic location has contributed to its growth as a major center for commerce and trade.

One of the key factors that has made Louisville/Jefferson County a major transportation hub is its extensive network of highways. The city is intersected by three major interstate highways - I-64, I-65, and I-71 - which connect Louisville to major cities such as Indianapolis, Cincinnati, and Nashville. These highways not only facilitate the movement of goods and materials but also attract distribution centers and logistics companies to the region.

In addition to highways, Louisville/Jefferson County also benefits from its proximity to the Louisville International Airport. The airport is a major cargo hub, handling large volumes of freight and serving as a key gateway for air cargo transportation in the region. The presence of the airport has attracted numerous freight forwarders, logistics providers, and e-commerce companies to establish their operations in Louisville/Jefferson County.

Fort Myers is a city located in southwest Florida, along the Gulf of Mexico. It is known for its beautiful beaches, vibrant downtown area, and rich history. One interesting fact about Fort Myers is that it was the winter home of Thomas Edison. Edison purchased a property in Fort Myers in 1885 and spent many winters there experimenting with new inventions. Today, visitors can tour his winter estate, which includes his laboratory and botanical gardens.

In terms of freight transportation, Fort Myers is well-connected to the rest of the state and the country. The city is served by several major highways, including Interstate 75 and US Route 41, which provide easy access to other cities in Florida and beyond. Additionally, Fort Myers has a deepwater port, the Port of Fort Myers, which handles a variety of cargo, including containerized goods, bulk materials, and breakbulk cargo. The port is an important hub for international trade and contributes to the local economy.