Located in the state of Kentucky, Louisville/Jefferson County is the largest city in the state and the 29th most populous city in the United States. The city is situated on the Ohio River, making it an important transportation hub for both freight and passenger traffic. The city's strategic location has contributed to its growth as a major center for commerce and trade.

One of the key factors that has made Louisville/Jefferson County a major transportation hub is its extensive network of highways. The city is intersected by three major interstate highways - I-64, I-65, and I-71 - which connect Louisville to major cities such as Indianapolis, Cincinnati, and Nashville. These highways not only facilitate the movement of goods and materials but also attract distribution centers and logistics companies to the region.

In addition to highways, Louisville/Jefferson County also benefits from its proximity to the Louisville International Airport. The airport is a major cargo hub, handling large volumes of freight and serving as a key gateway for air cargo transportation in the region. The presence of the airport has attracted numerous freight forwarders, logistics providers, and e-commerce companies to establish their operations in Louisville/Jefferson County.

South Bend is a city located in the state of Indiana, United States. It is the fourth-largest city in Indiana and is known for its rich history and diverse culture. The city was originally settled by Native American tribes, including the Potawatomi, Miami, and Sauk people. In the early 19th century, South Bend became an important transportation hub due to its location on the St. Joseph River, which provided access to the Great Lakes and the Mississippi River system. This made it a strategic location for the transportation of goods, including freight.

One of the key factors that contributed to South Bend's growth as a transportation center was the construction of the St. Joseph Valley Railroad in the 1850s. This railroad connected South Bend to other major cities in the region and facilitated the movement of goods and people. The city also became an important center for the manufacturing industry, with companies like Studebaker and Oliver Chilled Plow Works establishing their headquarters in South Bend. These companies relied heavily on freight transportation to distribute their products to markets across the country.

Today, South Bend continues to be an important transportation hub, with a well-connected network of highways, railways, and an international airport. The city's location at the crossroads of major transportation routes makes it an ideal location for businesses involved in freight transportation and logistics. South Bend is home to several logistics companies and distribution centers that play a crucial role in the movement of goods throughout the region and beyond.