South San Francisco, also known as "The Industrial City," is a vibrant city located in San Mateo County, California. It is situated on the San Francisco Peninsula, just south of the city of San Francisco. The city has a rich history dating back to the mid-19th century when it was primarily a rural agricultural area. However, with the advent of the railroad in the late 1800s, South San Francisco quickly transformed into a major industrial hub.

Freight transportation has played a significant role in the development and growth of South San Francisco. The city is home to one of the largest biotech clusters in the world, with numerous pharmaceutical and biotechnology companies located within its borders. These companies rely heavily on freight transportation to import raw materials and export finished products. The city is conveniently located near major transportation routes, including the San Francisco International Airport and the Port of Oakland, making it an ideal location for businesses involved in international trade.